This handsomely renovated, large, corner property, in the popular, Graduate Hospital area, is one of a kind. AKA 735 South 22nd Street, the home features 3600 square feet of living space, 7 fireplaces, 4 bay windows, and beautifully refinished, hardwood floors. 40 windows offer magnificent natural light throughout the day. Double flights of 7 limestone front steps with decorative wrought-iron railings welcome you. Entering, you step into a foyer with a central staircase, drenched in natural light. The main floor features a large living room with stained glass windows, a formal dining room, a powder room, and a cozy kitchen, recently renovated. Each of 4 bedroom suites, 2 on the 2nd floor and 2 on the 3rd, has its own, subway-tiled, 3-piece bathroom and large, walk-in closet. Between each pair of suites is a bonus sitting room. The bedrooms are located on opposite ends of the house for ultimate privacy. A pilot house gives access to a rooftop with a 360-degree view of the city skyline. The entire roof was completely redone in April 2015 and comes with a twelve year, fully transferable warranty. A bright, spacious basement, complete with a powder room and accessible by a door in the foyer and also by a separate side entrance to the street, would be ideal for a play room, media room, gym or professional home office. This rarely-offered property is located in the heart of the city, near cafes and restaurants and just minutes from public transportation and all that Center City has to offer. Walkers, runners and bikers can quickly reach the Schuykill River Trail via the South Street Bridge.